Selected Publications:
Lee, J. Implications of Liver Metastasis for Cancer Immunotherapy - Expert Insight. Immuno-Oncology Insights. 2022.
Sin J., Kashyap S., Acenas D., Cortez J., Lee, J., Marson A., Matloubian M., Waterfield M. ATF7ip Targets Transposable Elements for H3K9me3 Deposition to Modify CD8+ T Cell Effector and Memory Responses. Journal of Immunol. 2022. View in: PubMed
Huppert, L., Green, M., Kim, L., Chow, C., Leyfman, Y., Daud, A., Lee, J. Tissue-specific tregs in cancer metastasis: opportunities for precision immunotherapy. Cell Mol Immunol. 2021. View in: PubMed
Lee, J., Green, M., Huppert, L., Chow, C., Pierce, R., Daud, A. The Liver-Immunity Nexus and Cancer Immunotherapy. Clin Cancer Res. 2021. View in: PubMed
Lee, Y., Bogdanoff, D., Wang, Y., Hartoularos., Woo, J., Mowery, C., Nisonoff, H., Lee, D., Sun, Y., Lee. J. et al. XYZeq: Spatially-resolved single-cell RNA-sequencing reveals expression heterogeneity in the tumor microenvironment. Science Advances. 2021. View in: PubMed
Lee, J., Mehdizadeh, S., Smith, J., Young, A., Mufazalov, I., Mowery, C., Daud, A., Bluestone, J., Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasis. Science Immunology. 2020. View in: PubMed
Levine L., Mahuron K., Tsai K., Wu C, Mattis D., Pauli M., Oglesby , Lee J., Spitzer M., Krummel M., Algazi A., Rosenblum M., Alvarado , Daud A., Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma. Ann Surg Oncol. 2020. View in: PubMed
Chen Y., Huang W., Lin F., Hsieh H., Hsieh C., Hsieh R., Chen K., Yen M., Lee J., et al. Novel circulating tumor cell-based blood test for the assessment of PD-L1 protein expression in treatment-naïve, newly diagnosed patients with non-small cell lung cancer. Cancer Immunol Immunotherapy. 2019.
Lee, J.*, Bridge, J.*, Daud, A., Wells, J. W., & Bluestone, J. A. (2018). Cytokines, Chemokines, and Other Biomarkers of Response for Checkpoint Inhibitor Therapy in Skin Cancer. Frontiers in Medicine 2018.
Stamatouli, A., Quandt, Z., Perdigoto, A., Clark, P., Kluger, H., Weiss, S., Gettinger, S., Sznol, M., Young, A., Rushakoff, R., Lee, J. et al. Collateral Damage: Insulin-Dependent Diabetes Induced With Checkpoint Inhibitors. Diabetes. 2018.
Loo, K., Tsai, K., Mahuron, K., Liu, J., Pauli, M., Sandoval, P., Nosrati, A., K., Lee, J. et al. Partially Exhausted Cytotoxic Lymphocytes within the Tumor Microenvironment Predict Treatment Response to Mono or Combination Checkpoint Blockade in Melanoma. JCI Insight. 2017.
Holohan, D., Lee, J., Bluestone, J. Shifting the Evolving CAR T Cell Platform into Higher Gear. Cancer Cell. 2015.
Lee, J.*, Pegram, H.*, Hayman, E., Imperato, G., Tedder, T, and Brentjens, R. Tumor specific T cells modified to secrete IL-12 eradicate systemic tumors in the absence of prior toxic chemotherapy conditioning regimens. Blood. 2012.
Lee, J., Hayman, E., Pegram, H., Santos, E., Heller, G., Sadelain, M., Brentjens, R. In Vivo Inhibition of Human CD19 Targeted Effector T Cells by Natural Regulatory T Cells In A Xenotransplant Murine Model of B Cell Malignancy. Cancer Research. 2011.
Lee, J., Sadelain, M., Brentjens, R. “Retroviral Transduction of Murine Primary T Cells.” Genetic Modification of Hematopoietic Stem Cells. (Chapter 7) Humana Press. New York: New York. 2009.
Santos, E., Yeh, R., Lee, J., Nikhamin, Y., Punzalan, B., Larson, S., Sadelain, M., Brentjens, R. Highly Sensitive In Vivo Imaging of T cell Trafficking Utilizing a Membrane Bound Luciferase Enzyme Derived From Gaussia princeps. Nature Medicine. 2009.